TÜBİTAK Projects
1001 Research Projects
|
Assist.Prof. Deniz Yucel |
Histology Embryology |
Development of Layered, Tubular, Small-Medium Vascular Tissue by Tissue Engineering Methods |
Vasif Hasirci, Halime Kenar |
|
Assist.Prof. Nihan Unubol |
Vocational School of Health Services |
Development of antimicrobial catheters using peptide antibiotics and innovative surface binding strategies specific to biofilm forming bacteria |
Ozgul Gok, Tugba Ozal Ildeniz, Yesim Gurol, Tanil Kocago;z, Sesin Kocagoz, Tarik Eren |
|
Prof. Meltem Muftuoglu |
Medical Biotechnology |
Investigation of Effects of Mitochondria-targeted Drug-Loaded Nanocarrier Systems on Mismatch DNA Repair Mechanism Damaged Colon Cancer |
Yasemin Uzuner (Researcher), Ozgul Gok (Researcher), Devrim Ozarslan (Advisor), Meryem Sedef Erdal (Advisor) |
|
Assist.Prof. Meltem Kolgazi |
Physiology |
The Healing Effect of Akkermansia Muciniphila on Inflammation and Enteric Nervous System Degeneration Due to Chronic Colitis |
Serap Arbak (Researcher), Sinem Oktem Okullu (Researcher), Merve Acıkel Elmas (Researcher) |
|
Assist.Prof. Sinem Oktem Okullu |
Medical Microbiology |
Determination of Protein Profiles in Stomach Organoid Model Infected with H. Pylori Strains with Open and Closed Outer Membrane Inflammatory Protein A (Oipa) and Comparison of Protein Profiles Obtained by Maldi Imaging Method in Stomach Tissues Infected with Oipa Open and Closed Strains |
Aysel Ozpinar (Advisor), Arzu Tiftikci (Advisor), Umit Ince (Researcher), Aytac Erman (Researcher) Yasemin Ucal (Researcher) |
|
Assoc.Prof. Halime Kenar |
Medical Engineering |
Development of an In vitro Functional Human Heart Muscle-Coronary Vascular Model by Three-Dimensional Bioprinting |
Deniz Yucel(Advisor), Sadan Yavuz (Advisor), Ayse Karson (Researcher), |
|
Assist.Prof. Emel Baloglu |
Pharmacology |
Detection of Proteins Interacting with the Na+/K+-ATPase Pump in an Ischemic Heart Disease Model |
Zeynep Aslihan Durer (Advisor), Emre Deniz (Advisor), Evren Kilinc (Researcher), Emel Timucin (Researcher) |
|
Prof. Osman Ugur Sezerman |
Biostatistics and Medical Informatics |
Development of Diagnostic Methods and Creation of Appropriate Gene Panels for Primary Ciliary Dyskinesia (PSD) Patients in Turkey |
Ozlem Tugce Kaya (Researcher), Serap Sirvanci (Advisor), Sercin Karahuseyinoglu (Advisor), Cansin Sackesen (Researcher), Hasan Bayram (Researcher), Pinar Ata (Researcher), Ela Erdem Eralp (Researcher), Zeynep Seda Uyan (Researcher) |
|
Assoc.Prof. Emel Timucin |
Biostatistics and Medical Informatics |
Semi-Rational Peptide Design and Experimental Validations Targeting the AurorA A/N-Myc Complex |
Emel Baloglu (Researcher), Ozgur Kutuk (Researcher), Ozgur Gul (Researcher), Ahmet Can Timucin (Researcher), Koray Ozduman (Advisor) |
|
Assist.Prof. Yasemin Ucal |
Medical Biochemistry |
Biomarker Research in Hormone Receptor Positive Breast Cancer Tissues Evaluated in Different Risk Groups Based on Pam50 Test Result (220S105) |
Fatma Tokat (Researcher), Halil Kara (Researcher), Taner Korkmaz (Researcher), Aysel Ozpinar (Advisor), Umit Ince (Advisor), Cihan Uras (Advisor) |
|
Dr. Guralp Onur Ceyhan |
General Surgery |
Production of anti-CX3CR1 monoclonal antibody for use in the preclinical treatment of pancreatic cancer and chronic pancreatitis |
Guldal Suyen (Researcher), Tanil Kocagoz (Researcher), Elif Sever (Researcher), Ibrahim Hatipoglu (Researcher), Ihsan Ekin Demir (Advisor) |
|
Prof. Dr. Vasif Hasirci |
Medical Engineering |
Creating a Nervous Tissue Model on a Micropatterned Surface, Investigation of Axon Orientation and Nerve Damage Healing Processes |
Nesrin Hasirci (Researcher), Deniz Yucel (Researcher) |
|
Prof. Ali Osmay Gure |
Medical Biology |
Prognosis and Drug Susceptibility Biomarker Detection in Gastric Cancer Subgroups |
Secil Demirkol Canlı(Researcher) |
|
Assoc.Prof. Ahmet Bulut |
Computer Engineering |
Autonomous Management of Search Engine Advertising Campaigns |
|
|
Prof. Dr. Filiz Onat |
Medical Pharmacology |
Investigation of the Role of the Nigro-Striatal Dopaminergic Pathway in Epileptogenesis |
Rezzan Gulhan (Researcher), Umit Suleyman Sehirli (Researcher), Serap Sirvancı (Researcher), Medine Gulcebi (Researcher), Ozlem Akman (Researcher) |
1002 Quick Support Program
|
Assist.Prof. Yasemin Ucal |
Medical Biochemistry |
Investigation of Metabolite Profiles of Noninvasive Follicular Thyroid Neoplasm (NIFTP) with Papillary-Like Nuclear Characteristics by MALDI Imaging Mass Spectrometry Method |
Prof. Aysel Ozpinar (Researcher), Assist. Prof. Fatma Tokat (Researcher) |
|
Assoc.Prof. Ahmet Tarik Baykal |
Medical Biochemistry |
Biomarker Detection to Develop an Early Diagnostic Kit in Cervical Cancer |
Muhittin Abdulkadir Serdar (Researcher), Mete Gungor (Advisor), Ozguc Takmaz (Advisor) |
|
Assist.Prof. Merve Acikel Elmas |
Histoloji ve Embriyoloji ABD |
The Healing Effect of Aposine on Testicular Damage Caused by Monosodium Glutamate |
|
|
Prof. Mustafa Serteser |
Medical Biochemistry |
Development of Automated Micropipette Affinity Chromatography Analysis Method Alternative to Immunofixation Electrophoresis Analysis in Clinical Tests |
Betul Sahin (Researcher), Mete Bora Tuzuner (Researcher) |
1003 Priority Fields R&D Projects Support Program
|
Assoc.Prof. Ozge Can |
Medical Engineering |
Development of Antimicrobial Peptide and Similar Inspired by Nature |
Tanıl Kocagoz, Guldal Suyen, Serap Arbak, Tugba Arzu Ozal Ildeniz, Tarik Eren (Yildiz Teknik University), Deniz Baycin Hizal (Turgut Ilaclari A.S.), Ahmet Emin Atik , Recep Serdar Alpan, Yigit Erdemgil, Zeynep Zulfiye Yildirim Keles |
|
Assoc.Prof. Emel Timucin |
Biostatistics and Medical Informatics |
Machine Learning-Based New Gene Discovery and Development of a Drug Repositioning Platform for Improving Immunotherapy Efficacy in Cancer |
İlknur Melis Durasi (Researcher), Gunseli Bayram Akcapınar(Researcher), Gokcen Eren (Advisor) |
1505 University-Industry Cooperation Support Projects
|
Prof. Ali Osmay Gure |
Medical Biology |
Using Microrna-Based Biomarkers In Prediction Of The Window Of Endometrial Implant Using Minimally Invasive Methods |
Les Mikrogen Genetik Tani Merkezi Ltd.Sti. |
1512 Techno-enterprise Capital Support Program
|
Eda Tanoglu |
Project Office/ BİGG |
Acibadem University Bigghealth Program |
2515 COST European Cooperation Program in Science and Technology
|
Assoc.Prof. Ahmet Tarik Baykal |
Medical Biochemistry |
Peripheral Mitochondrial Dysfunction in Alzheimer's Disease |
Ebba Lohmann(Advisor), Hasmet Ayhan Hanagasi (Researcher), Zeynep Gamze Guven (Researcher), Gulsen Yildiz (Researcher) |
3501 National Young Researcher Career Development Projects
|
Assoc.Prof. Zeynep Aslihan Durer |
Biophysics (Medicine) Biochemistry (Pharmacy) |
Determination of functional differences of vinculin isoforms in muscle cells |
Devrim Oz Arslan, Beki Kan (Advisor), Zehra Sayers (Sabanci University, Advisor) |
|
Assist.Prof. Ozgul Gok |
Medical Engineering |
Development and In Vitro Evaluation of Vcam-1 Targeted Drug Delivery System for Reducing Oxidative Stress for the Treatment of Atherosclerosis |
Prof. Dr. Sahin Senay (Researcher), Yasemin Uzuner (Advisor) |
|
Assist.Prof. Zeynep Kanlidere |
Basic Pharmaceutical Sciences |
Preparation of Biocatalyst from Chemically Modified Oligonucleotides and Its Use in Enantioselective Carbohydrate Synthesis |
Sevgi Sarigul (Researcher) |
|
Assist.Prof. Elif Nedret Keskinoz |
Basic Medical Sciences, Anatomy |
Effects of Uridine Monophosphate (UMP), Choline, and Fish Oil Supplementation on Synaptogenesis in an Experimental Alzheimer's Disease Model |
Merve Acikel Elmas (Researcher), Serap Arbak (Advisor), Emel Ulupinar (Advisor), İsmail Hakki Ulus (Advisor) |
|
Assist.Prof. Nazli Keskin |
Molecular Biology and Genetics |
Comparison of the Effects of Hotspot Mutant P53 Proteins in Glioblastoma |
Mehmet Batu Erman (Advisor), Emre Deniz (Advisor) |
1001 Research Projects
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| Prof. Ahmet Ozbilgin (Celal Bayar University) | Medical Microbiology | Determination of the Molecular Mechanism of Gene Expression Regulation Responsible for the Development of Antimony Resistance in Leishmania Tropica | Ozgur Kurt ve Isın Akyar , Yusuf Ozbel (Ege University), Hatice Ertabaklar (Adnan Menderes University), Fadile Yildiz Zeyrek (Harran University), Mehmet Harman (Dicle University), Gulnaz Culha (Mustafa Kemal University), Ipek Ostan Ural (Celal Bayar University), Yavuz Yesilova (Harran University), Tanil Kocagoz (Advisor), Seray Ozensoy (Advisor, Ege University), Cumhur Gunduz (Advisor, Ege University) |
| Assoc. Prof. Ahmet Tarik Baykal | Medical Biochemistry | Investigation of the Onset of Neurodegenerative Mechanisms in a 5XFAD Transgenic Mouse Model of Alzheimer's Disease by Proteomics Methods | Mete Bora Tuzuner (Acibadem Labmed) |
| Prof. Ozgur Kurt | Medical Microbiology | Detailed genomic and proteomic characterization of the hybrid Leishmania donovani / L. infantum, which was first described in a domestic visceral leishmaniasis case in Turkey, and a comparative analysis of the pathogen effects and immune response in vivo in a mouse model with reference strains of L. Donovani and L. Infantum. | Sinem Oktem Okullu, Umit Ince, Fadile Yildiz Zeyrek, O.Ugur Sezerman, Ozge Can, Z.Tanil Kocagoz |
| Assist. Prof. Deniz Yucel | Histology Embryology | Development of Layered, Tubular, Small-Medium Diameter Vascular Tissue by Tissue Engineering Methods | Vasif Hasirci, Halime Kenar |
| Prof. Hasan Faruk Buyru | School of Medicine | Minimally Interventional Activation of Ovarian Follicles with Femtosecond Laser System in Premature Ovarian Failure | Ercan Bastu (Researcher), Bahar Yuksel Ozgor (Advisor), Onur Ferhanoglu (Advisor), Seydi Yavas (Advisor), Mehmet Burcin Umlu (Advisor) |
| Assist. Prof. Nihan Unubol | Vocational School of Health Services | Development of antimicrobial catheters using peptide antibiotics and innovative surface binding strategies specific to biofilm forming bacteria | Ozgul Gok, Tugba Ozal Ildeniz, Yesim Gurol, Tanil Kocagoz, Sesin Kocagoz, Tarik Eren |
| Assist. Prof. Sinem Oktem Okullu | Medical Microbiology | ABD | Determination of Protein Profiles in Stomach Organoid Model Infected with H. Pylori Strains with Open and Closed Outer Membrane Inflammatory Protein A (Oipa) and Comparison of Protein Profiles Obtained by Maldi Imaging Method in Stomach Tissues Infected with Oipa Open and Closed Strains | Prof. Aysel Ozpinar, Prof. Arzu Tiftikci, Prof. Umit Ince, Assoc. Prof. Aytac Erman, Assist. Prof. Yasemin Ucal |
1002 Quick Support Program
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| Instructor Ozgul Ozturk | Physical Therapy and Rehabilitation | DThe Effects of "Motion Observation" Method on Pain, Functional Level and Brain Hemodynamics in Patients with Trace Osteoarthritis | Assist. Prof. Sinem Burcu Erdogan (Researcher) |
| Assoc. Prof. Ozge Can | Medical Engineering | Developing a Method for Determining Antigen Binding Properties of Therapeutic Monoclonal Antibody in IgG Structure by Making Validations with the Surface Plasmon Resonance System | |
| Research Assistant Ecem Cengiz Orku | Nutrition and Dietetics | Determination of the Effects of Aspartame, Acesulfame K Saccharin and Sucralose Compounds on Glucose Tolerance | Prof. Murat Bas, Prof. Guldal Suyen |
1003 Priority Fields R&D Projects Support Program
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| M. Zeki Durak (Yildiz Technical University) | Medical Microbiology | Rapid and Sensitive Detection of Methicillin-Resistant Staphylococcus aureus (MRSA) and Vancomycin-Resistant Enterococci (VRE) Infections with the Surface Plasmon Resonance-Based Kit System | Isin Akyar Aysel Karatas (Acibadem Labmed Clinical Laboratories), Burcu Ekim (Gazi University), Onur Karatuna (Advisor), Aykutlu Dana (Advisor, Bilkent University) |
| Prof. Meltem Muftuoglu | Molecular Biology and Genetics | Development of novel 2-indolinone compounds as anti-interleukin 1 and chemotherapeutic drugs-Subproject 2: Development of DNA repair inhibitors as a new drug for the treatment of hereditary nonpolyposis colon cancer (MLH1 gene defect) | Cengiz Yakicier, Burak Erman (Koc University), Nilgun Karali (Istanbul University), Batu Erman (Sabanci University), Gokçe Cihan Ustundag (Istanbul University) |
| Prof. Ayşe Nurdan Tozun | School of Medicine | Flexible Robotic System for Endoscopy | Diler Kitapcioglu, Pelin Celikbilek Erkasap, Mehmet Emin Aksoy |
| Assist. Prof. Emre Deniz | Molecular Biology and Genetics | Genome-Level Screening and Modeling of Resistance Mechanisms Developed Against Cytotoxic Drugs in Cancer Treatments Using CRISPR/Cas9 Technology | Zeynep Tokcaer Keskin (Researcher), Meltem Muftuoglu (Advisor), Cengiz Yakicier (Advisor), Batu Erman (Advisor/Sabanci University) |
| Prof. Alp Dincer | School of Medicine | Development of a Diagnostic Product That Can Show the Genetic, Metabolic and Histopathological Characteristics of Glial Brain Tumors Non-invasively by Magnetic Resonance Imaging | Koray Ozduman, Alpay Ozcan, Ozge Can (Advisor), Esin Ozturk Isık (Bogazici University) |
| Assoc. Prof. Ozge Can | Medical Engineering | Development of Antimicrobial Peptide and Similar Inspired by Nature | Tanil Kocagoz, Guldal Suyen, Serap Arbak, Tugba Arzu Ozal Ildeniz, Tarik Eren (Yildiz Technical University), Deniz Baycin Hizal (Turgut Ilaclari A.S.), Ahmet Emin Atik , Recep Serdar Alpan, Yigit Erdemgil, Zeynep Zulfiye Yildirim Keles |
| Prof. Aysel Ozpınar | Medical Biochemistry | Developing a Clinical Screening System by Investigating the Role of Pericytes in Multiple Sclerosis Disease in Disease Subtypes | Assoc. Prof. Murat Kurtuncu, Assoc. Prof. Ahmet Tarik Baykal |
1505 University-Industry Cooperation Support Projects
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| Prof. Dr. Tanil Kocagoz | Medical Microbiology | Development of Cell Lines Producing Biosimilar TNF-Alpha Blocker | Meltem Muftuoglu, Ozge Can, Doruk Engin (Ankara Biotechnology Institute) |
1512 Techno-enterprise Capital Support Program
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| Aslı Semerci | Molecular Biology and Genetics | Developing a method for early diagnosis of Alzheimer's Disease by protein quantification analysis (Project no. 2150405) | Prof. Meltem Muftuoglu (Advisor) |
1601 Call Program
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| Seyma Merve Erdogan | Research Projects Office | Acibadem University BİGG Project | Duygu Tekin, Cengiz Kurtoglu |
2209-A University Students Research Projects Support Program
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| Tugçe Bozkurt | Molecular Biology and Genetics | Investigation of Molecule that Selectively Kills Hereditary Nonpolyposis Colon Cancer Cell Caused by MSH2 Gene Mutation | Prof. Meltem Muftuoglu (Advisor) |
| Çagla Akduman | School of Medicine | Epigenetic regulation of DNA repair genes in sporadic Alzheimer's disease | Prof. Meltem Muftuoglu (Advisor) |
2515 COST European Cooperation Program in Science and Technology
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| Assoc. Prof. Ahmet Tarik Baykal | Medical Biochemistry | Peripheral Mitochondrial Dysfunction in Alzheimer's Disease | Ebba Lohmann (Advisor), Hasmet Ayhan Hanagasi (Researcher), Zeynep Gamze Guven (Researcher), Gulsen Yildiz (Researcher) |
| Dr. Nafiye Cigdem Aktekin | Foreign Languages | Relationship of Intergenerational Solidarity with Family and School Components | Assist. Prof. Utkun Aydin (Advisor) , Dr. Hatice Celebi (Researcher) |
3001 Initial R&D Projects
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| Assist. Prof. Deniz Agirbasli | Medical Biology | Investigation of the relationship between vitamin D and leukocyte telomere length in postmenopausal women | Assoc. Prof. Meral Bayramoglu (Researcher / Expert), Prof. Meltem Muftuoglu (Advisor), Prof. Mustafa Cengiz Yakıcier (Advisor) |
| Prof. Ukke Karabacak | Nursing | Measurement Tool Development and Simulation for Intramuscular Drug Administration to the Ventrogluteal Area | Alper Karacan, Coskun Cengiz , Ozlem Dogu (Sakarya University), Ela Yilmaz Coskun (Namik Kemal University) |
| Assoc. Prof. Alpay Ozcan | Vocational School, Biomedical Device Technologies | Microstructure Simulations Obtained from Diffusion Magnetic Resonance Imaging and Modeling of Scanner Effects on Signal | |
| Assoc. Prof. Zeynep Aslihan Durer | Biophysics | Investigation of Specific Interaction Partners of the Atg3 Protein | Devrim Oz Arslan, Beki Kan, Emel Timucin (Advisor) |
3501 National Young Researcher Career Development Projects
| Project Coordinator | Department | Project Name | Project Team |
|---|---|---|---|
| Assist. Prof. Deniz Agirbasli | Medical Biology | Association of High-Density Lipoprotein-Cholesterol (HDL-K) Levels with Expression of Autophagy-Related Genes | Evren Kilinc, Devrim Oz Arslan (Advisor) |
| Assist. Prof. Sinem Oktem Okullu | Medical Microbiology | Identification of Possible Interaction Proteins Involved in the Binding of Outer Inflammatory Protein A (Oipa, Outer Inflammatory Protein A) to the Gastric Epithelial Surface, Known to be Effective in the Pathogenesis of Helicobacter Pylori and Has Vaccine Target Potential | Tanil Kocagoz, Ozge Can, Deniz Baycin (Turgut Ilac, Advisor) |
| Assoc. Prof. Zeynep Aslihan Durer | Biophysics (Medicine) Biochemistry (Pharmacy) | Determination of functional differences of vinculin isoforms in muscle cells | Devrim Oz Arslan, Beki Kan (Advisor), Zehra Sayers (Sabanci University, Advisor) |
| Proje Yürütücüsü | Anabilim Dalı/Bölümü | Projenin Adı | Proje Ekibi |
| Prof. Dr. Ali Osmay Güre | Tıbbi Biyoloji | Diyabet Hastalarında Görülen Algı, Öğrenme ve Hafıza Kayıplarıyla Ilgili Post-Transkripsyonel (Gen Ifadesi, RNA Değişimleri ve Düzenleyici Kodlamayan RNAlar) Moleküler Ağların Tespiti | |
| Doç. Dr. Fabienne Dumoulin | Tıp Mühendisliği | PDT, PTT ya da Işıkla Tetiklenen İlaç Salınımı İçin Tasarlanmış ve Kendiliğinden Düzenlenerek Ortogonal Fonksiyonlanabilen Karışık ya da Saf Ftalozomları Oluşturabilen Amfifilik Ftalosiyaninler | Ayşe Gül Gürek(Araştırmacı), Ümit İnci(Araştırmacı) |
| Prof. Dr. Alp Dinçer | Radyoloji | Kan Beyin Bariyer Bozulumu Için Atardamar Fırıl Etiketleme (Bbb-Asl) Tekniğinin Beyin Tümörlerinde Değerlendirilmesi (Jpnd "Debbie" Projesi- İş Paketi 5) | Esin Işık Öztürk(Araştırmacı), Ayça Erşen Danyeli(Araştırmacı), Koray Özduman(Araştırmacı) |